Leber’s hereditary optic neuropathy (LHON) is the most common mitochondrial disease, characterized by the painless loss of central vision. This condition primarily arises from mutations that affect Complex I of...

The fourth post on My 100 Top Tracks. Midnight Train to Georgia was an early release on the Buddah label after Gladys Knight switched to them from Motown. It's an obvious song of hers to choose but I love it. Another train song. A guy goes to LA to pursue stardom but the place proves 'too much for the man' and 'he...

The Fediverse, a network of interconnected social media services, requires users to choose a service for their account, tying their identity to that community. This can be problematic if the community experiences issues like spam, moderation problems, or shutdown. If we could decouple identity from community, like...

What started with an experiment of living without looking at social media turned into quitting it completely, changing my reading habits, and stopping consuming news daily. As the new step of decluttering my life, I am changing my approach to using services that heavily leverage algorithms to recommend new content,...

Antecedently: I get a weapon that I love more than my human grandchildren, we leave a big ol’ water-hole the hell alone, it’s time for a goddamn road-trip, and against...

I am not above judging books by their cover, and the snap impulse to snatch something up off a shelf and interrogate it deeply has brought me more joie de lire than just about any other way of discovering books; I occasionally get a good recommendation from a friend or fellow-reader, and more often than not fall...

He leído este post de THE_CHEI$ donde habla de cómo recuperó de un disco duro que creía desahuciado muchos recuerdos de su vida, sobre todo vídeos caseros. Y he caído en la cuenta de que no os he contado que he tenido un proceso semejante yo con varios discos duros de los que tenía por casa. Ya tenía un disco...

I have wanted to start my own history-related publication for a long time. I’ve worked for one long enough to know that it’s a large undertaking, which is why I’ve not actually pulled the trigger. But the time has come. I’m going to officially launch my second YouTube channel in a few weeks if all goes well. Like...

PyTorch 2.6 on Aurora ; source <(curl -L https://bit.ly/ezpz-utils) && ezpz_setup_env ; export CXX=$(which g++) ; export CC=$(which gcc) ; export REL_WITH_DEB_INFO=1 ; export USE_CUDA=0 ; export USE_ROCM=0 ; export USE_MKLDNN=1 ; export USE_MKL=1 ; export USE_ROCM=0 ; export USE_CUDNN=0 ; export USE_FBGEMM=0 ;...

Wissen gibt Kraft. Die drei Worte hat meine Schwiegertante heute rausgehauen, als wir uns während der Kommunionsparty von Katharinas Patenkind in Frankfurt für einen kleinen Plausch zurückgezogen hatten. Sie meinte damit das Gefühl der Fürsorge, das ein Museumsgang, ein Buch, ein Musikalbum oder ein Austausch mit...

The very brief version: “going to the cloud” can mean renting services/servers that you could get from anywhere. There’s little lock-in. The same four words “going to the cloud” might also mean locking your operations to a specific cloud provider, whose proprietary services will now be part of your business...